Table 1. BMI1P1 expression level in different AML subtypes.
Groups | Subtypes and stages | Subjects | BMI1P1 expression | P | ||
---|---|---|---|---|---|---|
Number | % | Median | Range | |||
Total AML | Total | 144 | 100 | 0.039 | 0–83.090 | < 0.001 |
N = 144 | FAB | |||||
M0 | 1 | 0.7 | 0.000 | — | — | |
M1 | 10 | 6.9 | 0.025 | 0–3.491 | < 0.001 | |
M2 | 52 | 36.1 | 0.040 | 0–12.191 | < 0.001 | |
M3 | 32 | 22.2 | 0.079 | 0–83.092 | < 0.001 | |
M4 | 29 | 20.1 | 0.030 | 0–35.430 | < 0.001 | |
M5 | 15 | 10.4 | 0.016 | 0–2.697 | < 0.001 | |
M6 | 5 | 3.5 | 0.169 | 0–17.308 | 0.018 | |
WHO | ||||||
AML with t(8;21) | 9 | 6.3 | 0.031 | 0–3.833 | < 0.001 | |
APL with t(15;17) | 30 | 20.8 | 0.079 | 0–83.092 | < 0.001 | |
AML with 11q23 translocation | 1 | 0.7 | 0.013 | — | — | |
AML without maturation | 9 | 6.3 | 0.021 | 0–3.491 | < 0.001 | |
AML with maturation | 42 | 29.2 | 0.046 | 0–12.791 | < 0.001 | |
Acute myelomonocytic leukemia | 29 | 20.1 | 0.030 | 0–35.430 | < 0.001 | |
Acute monoblastic and monocytic leukemia | 13 | 9.0 | 0.036 | 0–2.697 | < 0.001 | |
Acute erythroid leukemia | 4 | 2.8 | 0.101 | 0–17.308 | 0.046 | |
Control | 36 | 100 | 9.825 | 0–660.68 | — |
P: significance versus control.