Table 1. Associations of the expression of CD133 and CD44 with the demographic data and clinicopathological characteristics in HCC patients.
Variables | Cases | CD133 expression | P values | CD44 expression | P values | ||
---|---|---|---|---|---|---|---|
Low | High | Low | High | ||||
Age, years | |||||||
< 52 | 38 | 15 | 23 | 0.084 | 19 | 19 | 0.337 |
≥ 52 | 36 | 16 | 20 | 14 | 22 | ||
Sex | |||||||
Male | 64 | 24 | 40 | 1.000 | 27 | 37 | 0.502 |
Female | 10 | 7 | 3 | 6 | 4 | ||
HBsAg | |||||||
Negative | 11 | 10 | 1 | 0.444 | 4 | 7 | 0.294 |
Positive | 63 | 21 | 42 | 29 | 34 | ||
HBeAg | |||||||
Negative | 58 | 19 | 39 | 0.471 | 27 | 31 | 0.979 |
Positive | 16 | 12 | 4 | 6 | 10 | ||
Liver cirrhosis | |||||||
No | 13 | 7 | 6 | 0.006 | 7 | 6 | 0.460 |
Yes | 61 | 24 | 37 | 26 | 35 | ||
Tumor differentiation | 1.000 | 0.552 | |||||
I–II | 55 | 26 | 29 | 23 | 32 | ||
III–IV | 19 | 5 | 14 | 10 | 9 | ||
Tumor stage | 0.519 | 0.945 | |||||
I–II | 44 | 32 | 12 | 20 | 24 | ||
III–IV | 30 | 23 | 7 | 12 | 18 | ||
Tumor size | 0.305 | 0.066 | |||||
> 5 cm | 8 | 6 | 2 | 2 | 6 | ||
≦ 5 cm | 66 | 49 | 17 | 30 | 36 | ||
Tumor number | 0.960 | 0.404 | |||||
1–2 | 71 | 52 | 19 | 31 | 40 | ||
≥ 3 | 3 | 3 | 0 | 1 | 2 | ||
AFP1 (ng/ml) | 0.368 | 0.176 | |||||
< 40 | 48 | 28 | 20 | 24 | 24 | ||
≥ 40 | 26 | 3 | 23 | 9 | 17 | ||
ALT2 (U/l) | 0.301 | 0.243 | |||||
< 75 | 32 | 12 | 20 | 10 | 22 | ||
≥ 75 | 42 | 19 | 23 | 21 | 21 | ||
Child-Pugh | 1.000 | 1.000 | |||||
A | 70 | 27 | 43 | 31 | 39 | ||
B | 4 | 4 | 0 | 2 | 2 |
AFP, a-fetoprotein.
ALT, alanine aminotransferase.