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. 2016 Jun 23;7(30):47650–47662. doi: 10.18632/oncotarget.10258

Figure 2. High fat feeding does not promote increased proliferation in patient-derived xenograft tissue.

Figure 2

(A) Haematoxylin and eosin staining, dual immunohistochemistry of AMACR (red) and p63 (brown), cytokeratin 8/18 (red) and p63 (brown). Regions of cancer indicated by arrows, and benign glandular epithelium indicated by star in LFD and HFD xenograft tissue. (B) Immunolocalization of AR, PSA and Nkx3.1 in LFD and HFD xenografts. (C) Immunolocalization and percentage of Ki67 positive cells in LFD and HFD xenografts (n = 6 for LFD and n = 6 for HFD). Scale bars 100 μm in all images. Statistical analysis for panel C was by unpaired two-tailed t-test. Data are presented as the mean ± SEM.