Table 1. Biological parameters for diabetic rats treated with miR-27a inhibitor at week 12.

Variables	DM_miR-iNC (n = 7)	DM_miR-27ai (n = 7)
Scr (umol/L)	114.37 ± 7.56	67.25 ± 2.28*
Serum BUN (mmol/L)	15.63 ± 4.24	11.05 ± 1.52*
Blood glucose (mmol/L)	26.31 ± 1.36	25.70 ± 2.15
Urinary NAG (U/L)	35.37 ± 5.02	16. 38 ± 3.23#
UAER (ug/min)	1.45 ± 0.21	0.67 ± 0.06#
UACR (ug/mmol)	27.32 ± 2.32	15.35 ± 1.16#
Ccr (mL·min−1·Kg−1)	3.48 ± 0.45	7.37 ± 0.82#

DM_miR-iNC, diabetic rats treated with miRNA inhibitor negative control; DM_miR-27ai, diabetic rats treated with miR-27a inhibitor; Scr, serum creatinine; Serum BUN, serum blood urea nitrogen; Urinary NAG, urinary N-acetyl-β-D-glucosaminidase; UAER, urine albumin excretion rate; UACR, urine albumin to creatinine ratio; Ccr, creatinine clearance rate;

^*P < 0.01;

^#P < 0.001.