Table 2. Association between miRNA-200a expression and clinicopathologic features.
| Variables | No. of patients | miRNA-200a expression in cancer cells | miRNA-200a expression in stromal fibroblasts | ||||
|---|---|---|---|---|---|---|---|
| Low (%) | High (%) | p | Low (%) | High (%) | P | ||
| Gender | |||||||
| Male | 90 | 46 (51.1) | 44 (48.9) | 0.270 | 45 (50.0) | 45 (50.0) | 0.001 |
| Female | 44 | 18 (40.9) | 26 (59.1) | 9 (20.5) | 35 (79.5) | ||
| Age (years) | |||||||
| ≤63 | 72 | 28 (38.9) | 44 (61.1) | 0.027 | 28 (38.9) | 44 (61.1) | 0.722 |
| >63 | 62 | 36 (58.1) | 26 (41.9) | 26 (41.9) | 36 (58.1) | ||
| Pathologic type | |||||||
| Squamous carcinoma | 56 | 38 (67.9) | 18 (32.1) | 0.000 | 30 (53.6) | 26 (46.4) | 0.004 |
| Adenocarcinoma | 65 | 23 (35.4) | 42 (64.6) | 22 (33.8) | 43 (66.2) | ||
| Adenosquamous carcinoma | 7 | 1 (14.3) | 6 (85.7) | 2 (28.6) | 5 (71.4) | ||
| Large cell carcinoma | 6 | 2 (33.3) | 4 (66.7) | 0 (0) | 6 (100.0) | ||
| Pathologic differentiation | |||||||
| High | 10 | 8 (80.0) | 2 (20.0) | 0.589 | 3 (30.0) | 7 (70.0) | 0.854 |
| Median | 91 | 36 (39.6) | 55 (60.4) | 38 (41.8) | 53 (58.2) | ||
| Low | 33 | 20 (60.6) | 13 (39.4) | 13 (39.4) | 20 (60.6) | ||
| Clinical Stage* | |||||||
| I | 34 | 15 (44.1) | 19 (55.9) | 0.182 | 9 (26.5) | 25 (73.5) | 0.077 |
| II | 26 | 9 (34.6) | 17 (65.4) | 11 (42.3) | 15 (57.7) | ||
| IIIA | 74 | 40 (54.1) | 34 (45.9) | 34 (45.9) | 40 (54.1) | ||
| Vascular invasion | |||||||
| Negative | 120 | 60 (50.0) | 60 (50.0) | 0.131 | 50(41.7) | 70 (58.3) | 0.348 |
| Positive | 14 | 4 (28.6) | 10 (71.4) | 4 (28.6) | 10 (71.4) | ||