Table 3. Stratified analysis of age at diagnosis associated with gastric cancer patients' survival.
| Extremely young group | Young group | Elderly group | ||||
|---|---|---|---|---|---|---|
| Variable | Death/Patients (%) | HR (95% CI)a | Death/Patients (%) | HR (95% CI)a | Death/Patients (%) | Pb |
| Overall | 30/60 (50.0) | 0.78 (0.54-1.11) | 670/1342 (49.9) | 0.77 (0.71-0.83) | 5120/8690 (58.9) | |
| Sex | 0.033 | |||||
| Female | 13/26 (50.0) | 0.84 (0.48-1.45) | 280/554 (50.5) | 0.83 (0.73-0.94) | 1843/3280 (56.2) | |
| Male | 17/34 (50.0) | 0.74 (0.46-1.19) | 390/788 (49.5) | 0.73 (0.66-0.81) | 3277/5410 (60.6) | |
| Race | < 0.001 | |||||
| White | 18/38 (30.0) | 0.67 (0.42-1.06) | 430/805 (53.4) | 0.79 (0.72-0.88) | 3346/5437 (61.5) | |
| Black | 3/5 (60.0) | 1.26 (0.40-3.98) | 115/225 (51.1) | 0.74 (0.61-0.91) | 582/965 (60.3) | |
| Otherc | 9/17 (52.9) | 0.98 (0.51-1.89) | 125/312 (40.1) | 0.69 (0.57-0.83) | 1192/2288 (52.1) | |
| Tumor sites | 0.113 | |||||
| Cardia | 7/11 (63.6) | 0.65 (0.31-1.38)e | 169/322 (52.5) | 0.60 (0.51-0.70)e | 1480/2268 (65.3) | |
| Non-cardia | 17/35 (48.6) | 0.67 (0.41-1.09)e | 354/779 (45.4) | 0.67 (0.60-0.75)e | 2802/5021 (53.8) | |
| Otherd | 6/14 (42.9) | 0.53 (0.24-1.19) | 147/241 (61.0) | 0.84 (0.71-1.01) | 938/1401 (67.0) | |
| Histology | < 0.001 | |||||
| Intestinal | 4/7 (57.1) | 1.04 (0.39-2.80) | 67/160 (41.9) | 0.74 (0.58-0.95) | 1018/1971 (51.7) | |
| Diffuse | 17/33 (51.5) | 0.64 (0.39-1.03) | 349/649 (53.8) | 0.70 (0.62-0.79) | 1484/2283 (65.0) | |
| Other | 9/20 (45.0) | 0.76 (0.40-1.48) | 254/533 (47.7) | 0.73 (0.64-0.83) | 2618/4436 (59.0) | |
| TNM stage | < 0.001 | |||||
| I | 2/11 (18.2) | 0.85 (0.21-3.42) | 10/225 (4.4) | 0.17 (0.09-0.32) | 398/1725 (23.1) | |
| II | 4/9 (44.4) | 0.91 (0.34-2.44) | 90/285 (31.6) | 0.63 (0.51-0.78) | 976/2194 (44.5) | |
| III | 24/40 (60.0) | 0.60 (0.40-0.91) | 570/832 (68.1) | 0.74 (0.67-0.81) | 3746/4771 (78.5) | |
a
Univariate Cox regression, using the elderly group as referent.
b
Two-sided χ2 test for the frequency distributions of patients among the three groups.
c
Including American Indian, Alaska Native, Asian, Pacific Islander and Unknown.
d
Including Site overlapping, Unspecified and Unknown.
e
Multivariate Cox regression, adjusted for sex, race, histology and TNM stage.
HR, hazard ratio; CI, confidence interval.