Figure 3.

Distribution of the position of phenotypic and MMP alleles in the exons and protein domains of DAF-2. The C. elegans daf-2 exons (introns have been excluded) are shown at left in black and gray, with the corresponding protein domains in color on the right. Schematic style adapted from De Meyts and Whittaker (2002). Mutations from previous phenotypic screens can be seen, with missense mutations in red and nonsense mutations in black; MMP alleles can be seen in blue on the right. Asterisks indicate which of the MMP alleles were found to have novel dauer phenotypes in this study. While the exons and protein domains are shown to scale, the positions of the lines indicating individual mutations are approximate.