Table 2.
Two-year survival endpoints according to metabolic response at early PET-CT in different patients’ groups
| N° | Early metabolic response | Loco-regional PFS | Distant PFS | Global PFS | Overal survival | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Patients who underwent early PET-CT | 42 | R | 20 | 84.7% | p = 0.0007 | 70.7% | p = 0.0007 | 63.6% | p = 0.0002 | 73.5% | p = 0.01 |
| NR | 22 | 21.5% | 20.5% | 7.4% | 45.9% | ||||||
| Patients who underwent final PET-CT | 23 | R | 12 | 100% | p = 0.007 | 67.9% | p = 0.03 | 67.9% | p = 0.02 | 77.8% | p = 0.06 |
| NR | 11 | 35.4% | 30.5% | 15.2% | 62.3% | ||||||
| Patients who underwent surgery | 20 | R | 13 | 100% | p = 0.04 | 83.3% | p = 0.01 | 83.3% | p = 0.04 | 87.5% | p = 0.16 |
| NR | 7 | 41.7% | 42.9% | 28.6% | 66.7% | ||||||
R responder, NR non-responder, PFS progression free survival, PET-CT positron emission tomography-computed tomography