Table 2.
Correlation between parameters and the BDNF Val66Met polymorphism
| Parameter | Relative factor | Unstandardized coefficients | Standard error | Standardized coefficients | t | P |
|---|---|---|---|---|---|---|
| LG | ||||||
| BMI | WC | 0.118 | 0.020 | 0.296 | 5.924 | 0.000 |
| HC | 0.184 | 0.025 | 0.342 | 7.333 | 0.000 | |
| DBP | −0.498 | 0.227 | −0.072 | −2.193 | 0.029 | |
| FBG | Sex | 0.353 | 0.106 | 0.147 | 3.326 | 0.001 |
| TG | 0.391 | 0.122 | 0.143 | 3.217 | 0.001 | |
| WC | 0.012 | 0.006 | 0.093 | 2.094 | 0.037 | |
| SBP | Sex | 4.815 | 2.401 | 0.091 | 2.005 | 0.045 |
| DBP | TC | 1.879 | 0.586 | 0.143 | 3.208 | 0.001 |
| BMI | 0.484 | 0.162 | 0.133 | 2.995 | 0.003 | |
| PP | - | - | - | - | - | - |
| TC | DBP | 0.011 | 0.003 | 0.139 | 3.146 | 0.002 |
| Sex | 0.223 | 0.091 | 0.110 | 2.445 | 0.015 | |
| FBG | 0.088 | 0.038 | 0.103 | 2.306 | 0.022 | |
| Genotype | −0.132 | 0.063 | −0.093 | −2.090 | 0.037 | |
| TG | FBG | 0.058 | 0.016 | 0.159 | 3.556 | 0.000 |
| DBP | 0.004 | 0.001 | 0.108 | 2.425 | 0.016 | |
| HDL-C | BMI | −0.015 | 0.007 | −0.105 | −2.336 | 0.020 |
| LDL-C | DBP | 0.009 | 0.003 | 0.131 | 2.930 | 0.004 |
| Sex | 0.230 | 0.079 | 0.131 | 2.921 | 0.004 | |
| OG | ||||||
| BMI | WC | 0.090 | 0.037 | 0.054 | 2.427 | 0.016 |
| Sex | 0.730 | 0.144 | 0.121 | 5.062 | 0.000 | |
| DBP | 0.040 | 0.006 | 0.148 | 6.502 | 0.000 | |
| Age | 0.171 | 0.067 | 0.059 | 2.554 | 0.011 | |
| FBG | WC | −0.041 | 0.011 | −0.173 | −3.691 | 0.000 |
| DBP | −0.649 | 0.131 | −0.205 | −4.952 | 0.000 | |
| SBP | Age | 0.902 | 0.096 | 0.356 | 9.377 | 0.000 |
| BMI | 1.522 | 0.290 | 0.199 | 5.251 | 0.000 | |
| Sex | −4.215 | 1.751 | −0.091 | −2.407 | 0.016 | |
| DBP | BMI | 1.669 | 0.172 | 0.447 | 9.717 | 0.000 |
| Sex | −4.944 | 0.838 | −0.219 | −5.897 | 0.000 | |
| HC | −0.924 | 0.421 | −0.085 | −2.197 | 0.028 | |
| FBG | −0.651 | 0.235 | −0.105 | −2.767 | 0.006 | |
| PP | Age | 0.859 | 0.083 | 0.393 | 10.389 | 0.000 |
| TC | WC | −0.037 | 0.013 | −0.213 | −2.911 | 0.004 |
| Age | −0.013 | 0.005 | −0.105 | −2.670 | 0.008 | |
| BMI | 0.069 | 0.027 | 0.182 | 2.588 | 0.010 | |
| DBP | −0.008 | 0.004 | −0.084 | −2.065 | 0.039 | |
| TG | WC | 0.057 | 0.011 | 0.353 | 5.282 | 0.000 |
| Sex | −0.076 | 0.033 | −0.151 | −2.287 | 0.023 | |
| HDL-C | WC | −0.012 | 0.002 | −0.189 | −4.676 | 0.000 |
| Sex | 0.115 | 0.045 | 0.100 | 2.543 | 0.011 | |
| LDL-C | BMI | 0.113 | 0.014 | 0.328 | 7.871 | 0.000 |
| DBP | −0.012 | 0.004 | −0.125 | −2.996 | 0.003 | |
| CG | ||||||
| BMI | WC | 0.151 | 0.025 | 0.278 | 5.998 | 0.000 |
| Age | 0.247 | 0.079 | 0.084 | 3.123 | 0.002 | |
| FBG | WC | 0.186 | 0.055 | 0.137 | 3.359 | 0.001 |
| SBP | Age | −4.021 | 1.801 | −0.086 | −2.232 | 0.026 |
| HC | 0.706 | 0.152 | 0.181 | 4.631 | 0.000 | |
| DBP | Sex | 0.541 | 0.142 | 0.157 | 3.822 | 0.000 |
| FBG | −0.650 | 0.305 | −0.087 | −2.133 | 0.033 | |
| PP | Age | −3.783 | 1.391 | −0.104 | −2.720 | 0.007 |
| HC | 0.429 | 0.114 | 0.141 | 3.751 | 0.000 | |
| Sex | 4.185 | 1.404 | 0.113 | 2.980 | 0.003 | |
| TC | BMI | 0.045 | 0.020 | 0.149 | 2.310 | 0.021 |
| Age | −0.015 | 0.004 | −0.143 | −3.320 | 0.001 | |
| CC | −0.040 | 0.011 | −0.275 | −3.737 | 0.000 | |
| WC | 0.026 | 0.008 | 0.243 | 3.117 | 0.002 | |
| TG | BMI | 0.076 | 0.021 | 0.223 | 3.586 | 0.000 |
| Age | −0.027 | 0.005 | −0.233 | −5.740 | 0.000 | |
| FBG | 0.096 | 0.029 | 0.131 | 3.270 | 0.001 | |
| HC | −0.058 | 0.013 | −0.315 | −4.616 | 0.000 | |
| WC | 0.029 | 0.009 | 0.246 | 3.365 | 0.001 | |
| HDL-C | Sex | −0.003 | 0.001 | −0.108 | −2.688 | 0.007 |
| WC | −0.008 | 0.002 | −0.154 | −3.827 | 0.000 | |
| LDL-C | WC | 0.012 | 0.004 | 0.120 | 2.914 | 0.004 |
Abbreviations: LG long-lived group, OG offspring group, CG control group, WC waist circumference, HC hip circumference, CC chest circumference, BMI body mass index, FPG fasting plasma glucose, SBP systolic blood pressure, DBP diastolic blood pressure, PP pulse pressure, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol