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DAAs: Inhibitors of nucleocapsid assembly
| Drug name | Target | Compound | Stage of Development |
|---|---|---|---|
| GLS4 | Interfere with capsid formation/stability | Heteroaryldihydropyrimidine (HAPs) | Phase II |
| Bay 41-4109 | Viral nucleocapsid inhibitor | HAPs | Phase I |
| AT-130 | Inhibition of HBV capsid assembly | Phenylpropenamide derivatives | Preclinical and early clinical phase |
| NVR-3-778 (NVR1221) | Inhibition of HBV capsid assembly | Small molecule | Phase Ib |
