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Binding of HPV E6 to the second PDZ domain (PDZ2) from the human homologue of the Drosophila discs large tumor suppressor protein (hDlg). E6 (150 residues) consists of two zinc-binding domains (Cx2Cx29Cx2C). The bundle of 20 best E6 structures (residues 141 to 151, dark grey). Adopted and modified from [156], published under Creative Commons Attribution license.
