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. 2017 Jan 5;15:4. doi: 10.1186/s12951-016-0243-4

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — SEM observation and transdermal tests of CS-SeNPs in mice tissue. a Small intestine (a1) and skin (a2). N nucleus, NU nucleolus, C chromatin, RER rough endoplasmic reticulum, M mitochondria, VER vacuolization of the endoplasmic reticulum, GA Golgi apparatus, and PV pinocytic vesicle. The Se particles in the cell are marked with red arrows. b Comparison of the transdermal kinetics of the CS-SeNP and H₂SeO₃