Table 1.
Clinical characteristics of patients
| Previous chemotherapy
|
Total | ||
|---|---|---|---|
| + | − | ||
| Sex | |||
| Female | 7 | 9 | 16 |
| Male | 3 | 5 | 8 |
| Age in years (median) | 56–89 (64) | 55–83 (67) | 55–89 (67) |
| Smoking status | |||
| Never smoked | 6 | 8 | 14 |
| Current smoker | 2 | 2 | 4 |
| Former smoker | 2 | 1 | 3 |
| Unknown | 0 | 3 | 3 |
| Hepatitis virus | |||
| Hepatitis B virus antigen-positive | 0 | 0 | 0 |
| Hepatitis C virus antibody-positive | 1 | 0 | 1 |
| Alcohol consumption | |||
| Nondrinker | 8 | 7 | 15 |
| Social drinker | 1 | 3 | 4 |
| 0–20 g/daya | 0 | 0 | 0 |
| 20–40 g/daya | 1 | 1 | 2 |
| ≥40 g/daya | 0 | 0 | 0 |
| Unknown | 0 | 3 | 3 |
| Histology | |||
| Adenocarcinoma | 10 | 14 | 24 |
| EGFR mutation | |||
| Exon 18 G719X | 1 | 0 | 1 |
| Exon 19 deletion | 1 | 7 | 8 |
| Exon 21 L858R | 4 | 3 | 7 |
| None | 2 | 1 | 3 |
| Unknown | 2 | 3 | 5 |
| Operative and inoperative cases | |||
| Postoperative recurrent or metastatic cases | 4 | 6 | 10 |
| Inoperative advanced cases | 6 | 8 | 14 |
| Performance status | |||
| 0 | 8 | 7 | 15 |
| 1 | 2 | 4 | 6 |
| 2 | 0 | 1 | 1 |
| 3 | 0 | 2 | 2 |
| 4 | 0 | 0 | 0 |
| Metastasis or recurrence siteb | |||
| Bone | 3 | 5 | 8 |
| Pleurisy | 2 | 4 | 6 |
| Lung | 3 | 3 | 6 |
| Lymph node | 3 | 3 | 6 |
| Brain | 0 | 3 | 6 |
| Adrenal gland | 2 | 0 | 2 |
| Liver | 1 | 0 | 1 |
| Only tumor marker elevation | 2 | 0 | 2 |
Notes:
a
Alcohol consumption was converted into pure alcohol;
b
some overlap present.
Abbreviation: EGFR, epidermal growth-factor receptor.