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. 2017 Jan 5;18:4. doi: 10.1186/s12931-016-0486-5

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Validation of predicted target genes of miRNAs. The expression of predicted target genes of miRNAs in PBMCs of smokers and COPD patients was examined by qRT-PCR. Data are presented as 2^(−σσCt) relative to β-actin. ^* P < 0.05, ^** P < 0.01, ^*** P < 0.001 compared with smokers by Mann Whitney U test.