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. 2016 Sep 14;3(1):82–98. doi: 10.1016/j.jcmgh.2016.09.001

Figure 6.

Figure 6

Bone marrow transplants support role of non-hematopoietic cells in the inflammation of CD36KO mice. (A) Chimeric mice lacking CD36 on non-hematopoietic cells (WT→KO) show highest level of leukocytosis as compared with control chimeric groups (WT→WT) (P = .05) and (KO→KO) (P = .02). WBC, white blood cells. (B) Neutrophil levels are also highest in WT→KO as compared with WT→WT (P = .011) and with KO→KO (P = .05) groups. (C) MPO staining showing neutrophil infiltration in small intestines of WT→KO group and quantification of MPO+ cells in intestinal sections from 3 mice/group (P = .01). (D) Monocyte levels are highest in WT→KO as compared with WT→WT (P = .018) and KO→KO (P = .01) groups. (E) Levels of Gr-1low are increased in WT→KO as compared with KO→KO (P = .0001) and KO→WT (P = .009) groups (n = 4/chimeric mice per group). (A–E) representative of 2 experiments. Graphs show data as means ± SEM.