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. 2017 Jan 5;10:4. doi: 10.1186/s13045-016-0378-7

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Epidermal and endothelial damages caused by the infusion of CART cells. a Lichen striatus-like skin rashes appeared and worsened after the CART-EGFR therapy with the illustration of pathological changes such as the loss of partial epidermis, vacuolar degeneration of basal cells, and infiltration of numerous T lymphocytes in the epidermis and its appendages. b Diffused pinpoint hemorrhages and congestive rashes occurred on her neck, right upper arm, chest, left abdomen, and retropharyngeal mucosa after the CART133 cell infusion