Table 1.
Trial timeline
| Recruitment Day 1 | Days 2-6 | Day 7 | Day 14 | Day 21 | Follow up Day 28 | ||
|---|---|---|---|---|---|---|---|
| Recruitment | |||||||
| Pre-eligibility assessment | X | ||||||
| Informed consent obtained | X | ||||||
| Enrollment and randomisation | X | ||||||
| Dosage under supervision | X | ||||||
| Data collection | Format | ||||||
| Baseline questionnaire | Paper | X | |||||
| Adverse drug reactions | SMS/Online | X | |||||
| Sexual behaviour | SMS/Online | X | X | X | |||
| Other medications | SMS/Online | X | X | X | |||
| Drug adherence | SMS/Online | X | |||||
| Follow up questionnaire | Paper | X | |||||
| Specimen collection | Number | ||||||
| Self-collected swabs | 3 | X | |||||
| Self-collected swabs | 2 | X | |||||
| Test of cure swab | 1 | X | |||||
SMS short message service. 3 swabs collected at recuitment: 1 for whole genome sequencing if required, one for mRNA and 1 for culture. 3 swabs collected at follow up: 1 for whole genome sequencing if required, 1 for mRNA and one for test of cure