. 2017 Jan 5;10:8. doi: 10.1186/s13071-016-1932-4

Table 1.

Evaluation of TB effect of anti-rPSOP25 serum and mAb in mosquito feeding assays

	Immunization groups^a						Monoclonal antibody transfer groups^b
	Control mice			rPSOP25 immunized mice			Control mice			mAb transferred mice
	M1	M2	M3	M1	M2	M3	M1	M2	M3	M1	M2	M3
No. of mosquitoes infected/dissected	30/30	30/30	29/30	20/28	20/30	19/28	28/29	27/28	28/28	22/30	21/29	20/29
Prevalence of infection (%)^c	100	100	99.7	71.4	66.7	67.9	96.6	96.4	100	73.3	72.4	69.0
Mean prevalence (%)	99.9			68.7*					97.7			71.6*
Reduction in prevalence (%)^d						31.2						26.1
Oocyst intensity^e	90.7	86.8	90.5	25.2	22.1	21.7	97.1	96.3	94.3	29.8	34.2	33.7
SEM^f	11.58	11.17	12.50	5.890	5.232	5.138	13.47	13.66	11.82	5.462	6.373	6.800
Mean oocyst intensity			89.3			23.0*			95.9			32.6*
Reduction in oocyst intensity (%)^g						66.3						63.3

^aTB activity assay was carried out using rPSOP25-immunized mice

^bTB activity assay was carried out using BALB/C mice transferred with the anti-PSOP25 mAb

^cThe prevalence of infection was calculated by the number of mosquitoes with oocysts/total mosquitoes dissected in each group × 100%

^dThe percent reduction of prevalence was calculated as % mean prevalence _control – % mean prevalence _PSOP25

^eMean number of oocysts per mosquito midgut

^fStandard error of the mean

^gThe percent reduction in oocyst intensity was calculated as (mean oocyst intensity _control – mean oocyst intensity _PSOP25)/mean oocyst intensity _control × 100%

*P < 0.001 for comparisons between the experimental group and the control group