Table 1.

Comparison of demographic, lifestyle characteristics, serum lipid profiles and the genotype and allele frequencies of the SPTLC3 rs364585 SNP between the Han and Jing populations

Parameter	Han	Jing	t (x 2)	P
No. of patients	824	783
Male/female	405 / 419	389 / 394	0.045	0.832
Age (years)	57.27 ± 12.40	57.19 ± 12.50	0.122	0.903
Height (cm)	157.28 ± 8.27	158.08 ± 7.87	−1.984	0.047
Weight (kg)	56.35 ± 9.41	58.80 ± 10.09	−5.018	0.000
Body mass index (kg/m 2)	22.74 ± 3.19	23.46 ± 3.20	−4.517	0.000
Waist circumference (cm)	77.46 ± 8.90	80.38 ± 9.20	−6.647	0.000
Smoking status (n%)
0 g/day (non-smoker)	666 (80.8)	656 (83.8)
≤ 20 cigarettes/day	31 (3.8)	34 (4.3)
> 20 cigarettes/day	127 (15.4)	93 (11.9)	4.425	0.109
Alcohol consumption (n%)
0 g/day (non-drinker)	648 (78.6)	681 (87.0)
≤ 25 g/day	40 (4.9)	83 (10.6)
> 25 g/day	136 (16.5)	19 (2.4)	103.189	0.000
Systolic blood pressure (mmHg)	132.40 ± 18.90	132.18 ± 21.91	0.215	0.830
Diastolic blood pressure (mmHg)	81.78 ± 10.45	80.34 ± 10.30	2.778	0.006
Pulse pressure (mmHg)	50.62 ± 15.13	51.84 ± 17.81	−1.481	0.139
Glucose (mmol/l)	6.63 ± 1.06	6.86 ± 1.62	−3.390	0.001
Total cholesterol (mmol/l)	4.98 ± 0.85	5.08 ± 0.90	−2.286	0.022
Triglyceride (mmol/l)	1.39(0.67)	1.43(0.75)	−0.349	0.727
HDL-C (mmol/l)	1.80 ± 0.52	1.79 ± 0.46	0.419	0.676
LDL-C (mmol/l)	2.87 ± 0.44	2.82 ± 0.43	2.593	0.010
Apo A1 (g/l)	1.33 ± 0.20	1.28 ± 0.22	4.116	0.000
ApoB (g/l)	1.05 ± 0.24	1.04 ± 0.23	1.023	0.307
ApoA1/ApoB	1.32 ± 0.36	1.29 ± 0.38	1.481	0.139
Genotype [n(%)]
GG	223(27.1)	235(30.0)
GA	392(47.6)	371(47.4)
AA	209(25.4)	177(22.6)	2.501	0.286
Allele [n(%)]
G	838(50.9)	841(53.7)
A	810(49.1)	725(46.3)	2.622	0.105

HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, Apo Apolipoprotein. The value of triglyceride was presented as median (interquartile range), the difference between the two ethnic groups was determined by the Wilcoxon-Mann-Whitney test