Table 1.

First prenatal test, time of diagnosis and pregnancy outcome according to year of birth in cases with a common trisomy (T21, T18, T13)

	Year of birth
	2005–2006		2007–2009		2010–2012		Total
First prenatal test*
PNS1	47	37%	72	39%	87	46%	206	41%
PNS2	4	3%	52	28%	57	30%	113	22%
PND	29	23%	23	12%	14	7%	66	13%
No PNS or PND	48	38%	40	21%	30	16%	118	23%
Time of diagnosis**
Postnatally	52	41%	79	42%	71	38%	202	40%
Prenatally < 24 weeks	64	50%	104	56%	108	57%	276	55%
Prenatally > = 24 weeks	12	9%	4	2%	9	5%	25	5%
Pregnancy outcome***
Live birth	55	43%	79	42%	76	40%	210	42%
Fetal death	14	11%	15	8%	24	13%	53	11%
TOP	59	46%	93	50%	88	47%	240	48%

T21 trisomy 21, T18 trisomy 18, T13 trisomy 13, PNS1 prenatal screening in first trimester, PNS2 prenatal screening in second trimester, PND prenatal diagnosis, TOP termination of pregnancy

*X ² = 60.2, p < 0.001; X2 for trend = 23.5, p < 0.01

**X ² = 9.3, p = 0.054

***X ² = 2.4, p = 0.658