Table 2.

Effect of crude extract of the leaves of S. mitis on parasitaemia, percent suppression and survival time of P. berghei infected mice

Test substances	Dose (mg/kg)	% parasitaemia	%suppression	Survival time (day)
AE	200	31.65 ± 7.69	29.43 a3,c3,d3,e3	9.83 ± 1.32 a2,c2,d3,e3
	400	11.27 ± 4.05	74.86 a3,b3,d2,e3	12.33 ± 1.63 a3,b2,d3,e3
	600	2.01 ± 0.55	95.50 a3,b3,c2	17.50 ± 1.04 a3,b2,c3,e3
Vehicle	1 ml	44.85 ± 5.81	0.00	7.33 ± 0.81
CQ	25	0.00	100	27.50 ± 0.83
HE	200	28.45 ± 5.27	36.56a3,c3,d3,e3	10.83 ± 1.72a2,d3,e3
	400	8.30 ± 5.03	81.49a3,b3,e2	13.00 ± 2.00a3,e3,d2
	600	2.70 ± 1.10	93.97a3,b3	16.50 ± 1.04a3,b3,c2,e3
Vehicle	1 ml	44.85 ± 5.81	0.00	7.33 ± 0.81
CQ	25	0.00	100	27.50 ± 0.83

Data are expressed as mean ± SEM; n = 6; a = compared to distilled water (vehicle); b = compared to200 mg/kg; c = compared to 400 mg/kg; d = compared to 600 mg/kg; e = compared to chloroquine (25 mg/kg)

AE aqueous extract, CQ chloroquine, HE hydro-methanolic extract

¹ = p < 0.05, ² = p < 0.01, ³ = p < 0.001