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. 2017 Jan 5;17:13. doi: 10.1186/s12906-016-1529-7

Table 4.

Effect of fractions of leaves of S. mitis on percent parasitaemia, percent suppression and survival time on P. berghei infected mice

Test substances Dose (mg/kg) % parasitaemia % suppression Survival time (day)
NF 100 28.68 ± 6.31 42.11 a3,e3 11.33 ± 1.21a3,e3
200 28.31 ± 0.89 42.85 a3,e3 11.50 ± 1.76 a3.e3
400 32.81 ± 4.38 33.77 a3,e3 11.00 ± 1.54 a3,e3
CF 100 36.25 ± 2.14 26.84 a3,d3.e3 10.50 ± 0.54 a3,e3
200 33.83 ± 3.19 31.71a3,d1,e3 10.83 ± 0.75 a3,e3
400 29.86 ± 2.30 39.72 a3,b3,c1,e3 11.33 ± 1.03 a3,e3
AF 100 37.26 ± 1.84 24.78 a3,d3,e3 10.16 ± 1.47 a2,e3
200 36.10 ± 2.52 27.14a3,d2,e3 10.66 ± 1.36 a3,e3
400 32.46 ± 2.18 34.47 a3,b3,c2,e3 11.16 ± 0.75 a3,e3
Vehicle 1 ml 49.55 ± 2.53 0.00 7.33 ± 1.03
CQ 25 0.00 100 27.83 ± 0.75

Data are expressed as mean ± SEM; n = 6; a = compared to distilled water (vehicle); b = compared to100 mg/kg; c = compared to 200; d = compared to400 mg/kg; e = compared to chloroquine 25 mg/kg

CQ chloroquine, NF n-hexane fraction of crude hydro-methanolic extract, CF chloroform fraction of crude hydro-methanolic extract, AF aqueous fraction of Crude hydro-methanolic extract

1 = p < 0.05, 2 = p < 0.01, 3 = p = <0.001