Table 1.
Patient characteristics
| Variables | Without OSA | With OSA | P value |
|---|---|---|---|
| N (%) | 286 (29.5) | 685 (70.5) | |
| Age (years) | 56.5 ± 13.3 | 59.3 ± 11.7 | 0.001 |
| Male (%) | 71.7 | 78.4 | 0.016 |
| BMI (Kg/m2) | 24.6 ± 3.6 | 25.8 ± 4.1 | <0.001 |
| SBP (mm Hg) | 137.3 ± 20.4 | 137.4 ± 21.5 | 0.975 |
| DBP (mm Hg) | 79.3 ± 13.6 | 79.4 ± 14.3 | 0.926 |
| AHI | 1.7 ± 1.4 | 22.0 ± 16.7 | 0.001 |
| IVS (mm) | 10.7 ± 1.8 | 11.4 ± 2.3 | <0.001 |
| LVPW (mm) | 10.2 ± 1.8 | 10.5 ± 1.8 | 0.007 |
| HbA1c (%) | 6.1 ± 1.1 | 6.3 ± 1.2 | 0.029 |
| Creatinine (μmol/L) | 91.6 ± 48.0 | 99.0 ± 65.9 | 0.098 |
| BUN (mmol/L) | 5.5 ± 3.2 | 5.8 ± 2.8 | 0.162 |
| FPG (mmol/L) | 6.2 ± 2.6 | 6.5 ± 3.0 | 0.130 |
| Triglyceride (mmol/L) | 1.9 ± 0.3 | 1.8 ± 0.1 | 0.582 |
| Total cholesterol (mmol/L) | 4.5 ± 1.3 | 4.5 ± 1.2 | 0.643 |
| LDL-C (mmol/L) | 2.7 ± 1.0 | 2.7 ± 1.0 | 0.939 |
| HDL-C (mmol/L) | 1.0 ± 0.3 | 1.0 ± 0.2 | 0.961 |
| Proteinuria (%) | 17.1 | 20.4 | 0.183 |
| Diabetes mellitus (%) | 19.6 | 24.4 | 0.061 |
| Dyslipidemia (%) | 10.5 | 14.6 | 0.052 |
| Aortic dissection (%) | 20.3 | 19.9 | 0.472 |
| Aneurysm (%) | 4.5 | 5.4 | 0.354 |
| CHD (%) | 37.4 | 41.9 | 0.110 |
| Cerebrovascular disease (%) | 6.6 | 9.9 | 0.063 |
| Heart failure (%) | 19.2 | 21.9 | 0.200 |
| Atrial fibrillation (%) | 8.4 | 9.1 | 0.424 |
| HCM (%) | 1.7 | 3.4 | 0.121 |
| Anti-platelet (%) | 49.0 | 54.3 | 0.073 |
| Statins (%) | 59.1 | 66.9 | 0.013 |
| ACEI (%) | 22.0 | 22.0 | 0.534 |
| ARB (%) | 49.7 | 46.0 | 0.165 |
| Beta-blocker (%) | 59.4 | 66.4 | 0.023 |
| Alpha-blocker (%) | 6.6 | 6.4 | 0.500 |
| CCB (%) | 55.2 | 57.1 | 0.324 |
| Diuretic (%) | 16.1 | 18.7 | 0.192 |
| Warfarin (%) | 6.6 | 7.2 | 0.448 |
Denote: BUN blood uria nitrogen, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, CHD coronary heart disease, HCM hypertrophy cardiomyopahty, ACEI angiotensin converting enzyme inhibitor, ARB angiotensin receptor blocker, CCB calcium channel blocker