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Vcan and HA accumulation induced by poly(I:C) (pIC) is attenuated in Vcan−/− mice. HA (A–D) and Vcan (E–H) staining on adjacent lung tissue sections of control (A, C, E, and G) and Vcan−/− (B, D, F, and H) mice treated with PBS (A, B, E, and F) and poly(I:C) (C, D, G, and H) demonstrate that Vcan and HA accumulation induced by poly(I:C) in control mice is attenuated in Vcan−/− mice.
