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Leukocyte infiltration into lungs in response to poly(I:C) (pIC) instillation. A, instillation of poly(I:C)-induced leukocyte infiltration into lungs associated with regions of Vcan accumulation in control mice, which was diminished in Vcan−/− mice. B, consistently, total leukocyte numbers in BALF were significantly decreased in Vcan−/− mice. n = 9–17 mice/group. **, p < 0.01; ***, p < 0.001. Error bars, S.D.
