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Expression of inflammatory cytokines and chemokines in response to poly(I:C) (pIC) instillation in lungs. PIC instillation induced increases in inflammatory cytokines and chemokines, such as TNFα, IL1β, Cxcl2, IFNα, IFNγ, and IL10, in whole lungs of control mice, which were attenuated in Vcan−/− mice. n = 8–17 mice/group. *, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001. Error bars, S.D.
