Gene expression of versican, inflammatory cytokines, and chemokines in cultured lung fibroblasts in response to poly(I:C) (pIC). PIC treatment induced increases in total versican as well as IL1β in primary cultured lung fibroblasts from control mice, which was significantly reduced in Vcan−/− fibroblasts. *, p < 0.05; **, p < 0.01. Results are mean values from each independent experiment run in triplicate each time. n = 5 independent experiments from lung fibroblasts established from 5 mice/group. Error bars, S.E.