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. 2016 Nov 16;292(1):82–99. doi: 10.1074/jbc.M116.750950

FIGURE 8.

FIGURE 8.

Knockdown of JARID2 cancelled MEG3-mediated changes in the expression of part of EMT-related genes in A549 and LC-2/ad cells. QRT-PCR analysis was performed to detect the expression of CDH1/E-cadherin, FN1/fibronectin, vimentin, ZEB1, ZEB2, miR-200a, miR-200c, and JARID2 in A549 (A) and LC-2/ad (B) cells infected with the control retrovirus or the retrovirus expressing MEG3 and/or the retrovirus expressing JARID2 shRNA without or with treatment of TGF-β for 24 h (*, p < 0.01 compared with control; **, p < 0.05 compared with control; ***, p < 0.01 compared with the sample without TGF-β treatment; ****, p < 0.05 compared with the sample without TGF-β treatment).