Table 2.

Univariable and multivariable analyses of the association between SHPT and progression of aortic valve calcification

	Univariable analysis		Multivariable analysis
	β Coeff. ± SE	P-value	β Coeff. ± SE	Partial r2	P-value	Total r2
AVC progression, AU
SBP, mmHg	0.29 ± 2.53	0.004	0.34 ± 2.61	0.12	0.001	0.28
SHPT	0.27 ± 92.9	0.006	0.36 ± 97.9	0.12	0.001	0.28
Isolated SHPT	0.30 ± 93.9	0.002	0.38 ± 96.1	0.14	<0.0001	0.30
AVCdensity progression, AU/cm2
SBP, mmHg	0.31 ± 0.60	0.002	0.34 ± 0.63	0.11	0.001	0.26
SHPT	0.29 ± 21.9	0.004	0.36 ± 23.7	0.11	0.001	0.26
Isolated SHPT	0.32 ± 22.1	0.001	0.37 ± 23.1	0.13	<0.0001	0.28

β coeff. are standardized regression coefficient; partial r² are coefficient of partial determination; total r² are the overall r² of the multivariable model. The multivariable analysis is adjusted for age, sex, dyslipidaemia, diabetes, metabolic syndrome, antihypertensive medication, creatinine level, baseline AS severity (i.e. peak aortic jet velocity), and square root of baseline aortic valve calcification.

AVC, aortic valve calcification; AVC_density, aortic valve calcification indexed to cross-sectional area of the aortic annulus; SBP, systolic blood pressure; other abbreviations as in Table 1.