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. 2016 Nov 10;16(1):8–22. doi: 10.1074/mcp.M116.061481

Table III. Prediction of transcription factors by UR analysis (IPA software) in HT-29 cells treated with GI50, TGI and LC50 concentrations of CA and CS for 24 hours.

GI50
TGI
LC50
TFa z-score p value Proteins TFa z-score p value Proteins TFa z-score p value Proteins
CA NFE2L2 2.889 7.72·10−11 UGDH, TXNRD1, SQSTM1, SLC2A1, PSAT1, PGD, ME1 GCLM, GCLC, G6PD, AKR1B10 NFE2L2 3.193 1.33·10−12 UGDH, TXNRD1, SQSTM1, SLC2A1, PSAT1, PGD, ME1, GCLM, GCLC, G6PD, AKR1B10 NFE2L2 3.028 1.80·10−11 UGDH, TXNRD1, SRXN1, SQSTM1, PSAT1, PGD, ME1, HSPA9,HSP90B1, GCLM, GCLC, AKR1B10
E2F1 −2.000 5.83·10−8 UGDH, TOP2A, RRM1, COPS8, PSAT1, SLC3A2, STMN1, TXNRD1 ATF4 2.611 3.27·10−11 WARS, SLC3A2, SARS, PSAT1, HSPA5, HSP90B1, ASNS, AARS, GARS
XBP1 2.417 7.52·10−7 SSR4, SSR1, SEC61B, HYOU1, HSPA5, HSP90B1
CS NFE2L2 2.756 1.80·10−9 TXNRD1, SQSTM1, PSMC3, PSMC1, PSMA7, HSP90AA1, GCLM, AKRQB10 NFE2L2 2.799 4.84·10−11 TXNRD1, SQSTM1, PSMD1, PSMC1, PSMA4, PSAT1, ME1, HSP90AA1, GCLM

a TF, Transcription Factor.