Table 5.

Multivariable linear regression evaluating the association of MetS components and secondary neuropathy outcome measures

Variable	IENFD leg Parameter estimate (m/s) (95%CI)	Sural amplitude Parameter estimate (uV) (95%CI)	Tibial amplitude Parameter estimate (mV) (95%CI)	Ulnar amplitude Parameter estimate (uV) (95%CI)
Age	−0.05 (−0.09,0.001)	−0.17 (−0.34,0.001)	−0.12 (−0.23,−0.02)*	−0.52 (−0.72,−0.32)*
Male (reference female)	−1.89 (−3.35,−0.43)*	0.84 (−4.46,6.15)	0.60 (−2.68,3.88)	−9.96 (−16.19,−3.73)*
Height unit=5 cm	−0.04 (−0.39,0.30)	−1.25 (−2.51,0.01)	−0.34 (−1.12,0.44)	−0.49 (−1.97,0.99)
Pre-diabetes (reference normal)	−0.09 (−1.18,0.99)	2.46 (−1.47,6.4)	−0.92 (−3.35,1.51)	0.18 (−4.44,4.80)
Diabetes (reference normal)	−1.39 (−2.61,−0.17)*	−3.64 (−8.07, 0.79)	−1.19 (−3.93,1.55)	−4.03 (−9.24,1.17)
Waist Circumference unit=5 cm	0.03 (−0.16,0.21)	−0.54 (−1.21,0.12)	−0.51 (−0.92,−0.10)*	−0.36 (−1.14,0.43)
SBP unit=10 mm Hg	0.09 (−0.25,0.43)	−0.53 (−1.76,0.70)	−0.23 (−0.99,0.53)	0.07 (−1.38,1.51)
Triglycerides unit=50 mg/dL	−0.23(−0.56,0.10)	0.04 (−1.15,1.23)	−0.04 (−0.77,0.70)	0.18 (−1.22,1.58)
HDL unit=10 mg/dL	−0.56 (−1.03,−0.10)*	−1.97 (−3.66,−0.28)*	−0.40 (−1.44,0.65)	−1.71 (−3.7,0.28)

^*p<0.05

IENFD= nerve fiber density, SBP=systolic blood pressure