Figure 1.

Regulatory T cell (T_reg) clonotype overlap between stem cell donor and recipient. High‐throughput T cell receptor (TCR)‐α chain sequencing was used to define distinct T_reg clonotypes. Shown are Venn diagrams illustrating overlap in the 100 most frequent T_reg clonotypes found in donor‐derived T_reg before (yellow), after ex‐vivo expansion (red) and the recipient prior to T_reg infusion (blue). Upper diagram = patient 1, lower diagram = patient 2. Numbers illustrate numbers of distinct T_reg clonotypes.