Table 3.
Cell type/source | Sample/time‐point | Cell number ×106 | Read number ×106 | Clonotype count | |
---|---|---|---|---|---|
Patient 1 | Donor Treg | Isolated Treg | 0·040 | 0·25 | 6804 |
Donor Treg | Expanded Treg | 4·300 | 21·03 | 47 452 | |
Patient Treg | Preinfusion | 0·004 | 0·08 | 866 | |
Patient Treg | 24 h post | 0·066 | 0·67 | 19 984 | |
Patient Treg | 1 week post | 0·081 | 0·93 | 19 134 | |
Patient Treg | 2 weeks post | 0·116 | 2·06 | 31 703 | |
Patient Treg | 3 weeks post | 0·078 | 1·93 | 11 154 | |
Patient Treg | 6.5 weeks post | 0·040 | 0·64 | 11 157 | |
Patient CD8 | Preinfusion | 0·470 | 5·98 | 7949 | |
Patient CD8 | 24 h post | 0·510 | 6·77 | 9547 | |
Patient CD8 | 1 week post | 0·900 | 8·42 | 17 370 | |
Patient CD8 | 2 weeks post | 0·880 | 10·50 | 7401 | |
Patient CD8 | 3 weeks post | 1·220 | 21·39 | 11 544 | |
Patient CD8 | 6.5 weeks post | 1·400 | 20·52 | 15 489 | |
Patient CD4 | Preinfusion | 0·003 | 0·03 | 762 | |
Patient CD4 | 24 h post | 0·005 | 0·05 | 1165 | |
Patient CD4 | 1 week post | 0·008 | 0·07 | 5780 | |
Patient CD4 | 2 weeks post | 0·007 | 0·12 | 2052 | |
Patient CD4 | 3 weeks post | 0·010 | 0·23 | 4419 | |
Patient CD4* | 6.5 weeks post | 0·008 | 0·01 | 2103 | |
Patient 2 | Donor Treg | Isolated Treg | 0·123 | 1·30 | 6810 |
Donor Treg | Expanded Treg | 2·560 | 12·80 | 3621 | |
Patient Treg | Preinfusion | 0·072 | 0·30 | 2957 | |
Patient Treg | 1 week post | 0·270 | 6·23 | 30 152 | |
Patient Treg | 5 weeks post | 0·199 | 1·04 | 1535 |
*Sample excluded from analysis for quality reasons. Treg = regulatory T cells.