Table 4.

Gene ontology analysis: top diseases and functions

ID	Top diseases and functions	Molecules in network
1	Cell cycle, cellular assembly and organization, DNA replication, recombination, and repair	ABCG2, alcohol group acceptor phosphotransferase, ALT, ASAH1, AURKA, BUB1, BUB1B, CCNA2, CCNB1, CD163, Cdc2, CDC25A, CDK1, Cyclin B, ENO2, GADD45A, GINS1, HISTONE, Histone H1, Histone h3, HOPX, IL6, MCM4, MT1G, NASP, NCAPG, PRC1, PRPF4B, PTPase, RNA polymerase II, SFPQ, SMC4, SNX10, Sod, TTK
2	Cell cycle, embryonic development, organismal survival	AIM2, APC (complex), ATM/ATR, ATR, CDC6, CDC20, Cdk, Cyclin A, Cyclin D, Cyclin E, DTL, Dynein, E2f, FANCI, GMNN, HERC5, LUC7L3, MAD2L1, MCM10, MELK, NBN, NFkB (complex), NUSAP1, PCNA, PPP4R4, Rb, Rfc, RFC3, RFC4, RPA, RRM2, SKP2, TRIM22, TYMS, UNG
3	Antimicrobial response, inflammatory response, cell signaling	2′ 5′ oas, DDX58, DDX60, EIF2AK2, ERK, IFI16, IFI44, IFIH1, IFIT1, IFIT3, IFIT5, Ifn, IFN alpha/beta, IFN Beta, IFN type 1, Ifnar, IRF, ISG15, ISG20, ISGF3, JAK, MT1M, MX1, Oas, OAS1, OAS2, PARP12, RSAD2, STAT4, Stat1‐Stat2, THEMIS2, USP18, XAF1, ZC3HAV1
4	Nervous system development and function, cancer, organismal injury and abnormalities	ACKR3, ACPP, ADAMTS1, ADCY, ADRB, Alpha catenin, AREG, BNIP3, CAP2, Cg, Creb, DUSP2, EMR2, FGF13, FSH, Gpcr, GPR56, GPR65, Hdac, HRH1, Lh, Mapk, Metalloprotease, MT1F, MT1X, NMDA Receptor, OXTR, Pdgfr, PLC, PVR, SLC7A11, SNAP25, STEAP1, TCF, Vegf
5	Infectious disease, cell morphology, hair and skin development, and function	AIF1, Akt, c‐Src, Calcineurin A, Collagen(s), CYR61, Fascin, FCGR2B, FERMT1, Fgf, Fibrin, Fibrinogen, GDF15, Integrin, Integrin alpha 3 beta 1, Integrin alpha 4 beta 1, ITGA1, JINK1/2, KIAA0101, Laminin, Lfa‐1, LRIG1, MAP2K1/2, MT1E, Notch, PBK, PMAIP1, PNISR, PNN, PPIG, SLC4A7, TLR2/TLR4, TRIB3, TRIM5, ZWINT