FIG. 2.

Suppression of Vpr-induced cell cycle G₂ arrest by Hsp16 mimics cellular heat shock responses. (A) Induction of cellular heat shock responses suppresses Vpr-induced G₂ arrest as indicated by prevention of the Vpr-induced cell elongation (a) and growth delay (b). Cellular heat shock responses were triggered either by an acute heat treatment (45°C for 15 min) or constant high temperature at 36°C. (B) Induction of cellular heat shock responses does not affect the protein levels of Vpr as indicated by Western blot analysis. GI, gene induction.