Table 3. Characteristics of hospitalized stroke patients with and without COPD.
| Number | No COPD | COPDne | COPDe | P valuea | P valueb | |||
|---|---|---|---|---|---|---|---|---|
| 230553 | 38997 | 7924 | ||||||
| Gender | n | (%) | N | (%) | n | (%) | <0.0001 | <0.0001 |
| Female | 101287 | (43.9) | 13431 | (34.4) | 2071 | (26.1) | ||
| Male | 129266 | (56.1) | 25566 | (65.6) | 5853 | (73.9) | ||
| Age, years | <0.0001 | <0.0001 | ||||||
| 40–49 | 27378 | (11.9) | 1032 | (2.7) | 96 | (1.2) | ||
| 50–59 | 50929 | (22.1) | 3186 | (8.2) | 362 | (4.6) | ||
| 60–69 | 59344 | (25.7) | 7577 | (19.4) | 1074 | (13.6) | ||
| 70–79 | 61397 | (26.6) | 16071 | (41.2) | 3314 | (41.8) | ||
| ≥80 | 31505 | (13.7) | 11131 | (28.5) | 3078 | (38.8) | ||
| Low income | 9701 | (4.2) | 2354 | (6.0) | 604 | (7.6) | <0.0001 | <0.0001 |
| Types of stroke | <0.0001 | <0.0001 | ||||||
| Hemorrhage | 48159 | (20.9) | 5603 | (14.4) | 1014 | (12.8) | ||
| Ischemia | 142082 | (61.6) | 24313 | (62.4) | 4774 | (60.3) | ||
| Other | 40312 | (17.5) | 9081 | (23.3) | 2136 | (27.0) | ||
| Stay in teaching hospital | 210345 | (91.2) | 33339 | (85.5) | 6526 | (82.4) | <0.0001 | <0.0001 |
| Medical conditions | ||||||||
| Hypertension | 107302 | (46.5) | 22633 | (58.0) | 4430 | (55.9) | <0.0001 | 0.0005 |
| Mental disorder | 34402 | (14.9) | 10402 | (26.7) | 2280 | (28.8) | <0.0001 | 0.0001 |
| Diabetes | 55695 | (24.2) | 9661 | (24.8) | 1826 | (23.0) | 0.0015 | 0.0011 |
| Congestive heart failure | 5683 | (2.5) | 3385 | (8.7) | 1223 | (15.4) | <0.0001 | <0.0001 |
| Traumatic brain injury | 13100 | (5.7) | 3555 | (9.1) | 867 | (10.9) | <0.0001 | <0.0001 |
| Dementia | 6758 | (2.9) | 2623 | (6.7) | 687 | (8.7) | <0.0001 | <0.0001 |
| Hyperlipidemia | 15563 | (6.8) | 3340 | (8.6) | 454 | (5.7) | <0.0001 | <0.0001 |
| Anemia | 4996 | (2.2) | 1668 | (4.3) | 386 | (4.9) | <0.0001 | 0.0185 |
| Atrial fibrillation | 2981 | (1.3) | 1241 | (3.2) | 330 | (4.2) | <0.0001 | <0.0001 |
| Liver cirrhosis | 2606 | (1.1) | 593 | (1.5) | 144 | (1.8) | <0.0001 | 0.0529 |
| PVD | 2305 | (1.0) | 649 | (1.7) | 131 | (1.7) | <0.0001 | 0.9442 |
| Renal dialysis | 4042 | (1.8) | 545 | (1.4) | 111 | (1.4) | <0.0001 | 0.9820 |
| Obesity | 798 | (0.4) | 156 | (0.4) | 29 | (0.4) | 0.2494 | 0.6592 |
| Smoking cessation | 121 | (0.1) | 59 | (0.2) | 7 | (0.1) | <0.0001 | 0.1728 |
| Number of medical conditions | <0.0001 | <0.0001 | ||||||
| 0 | 70929 | (30.8) | 7032 | (18.0) | 1422 | (18.0) | ||
| 1 | 91344 | (39.6) | 13952 | (35.8) | 2612 | (33.0) | ||
| 2 | 46512 | (20.2) | 10486 | (26.9) | 2142 | (27.0) | ||
| 3 | 16322 | (7.1) | 5165 | (13.2) | 1162 | (14.7) | ||
| ≥4 | 5446 | (2.4) | 2362 | (6.1) | 586 | (7.4) | <0.0001 | <0.0001 |
| Lipid-lowering agents | 40662 | (17.6) | 8084 | (20.7) | 1593 | (20.1) | <0.0001 | 0.2090 |
| Anti-platelet agents | 110643 | (48.0) | 26503 | (68.0) | 5869 | (74.1) | <0.0001 | <0.0001 |
| Anticoagulant | 5008 | (2.2) | 1424 | (3.7) | 423 | (5.3) | <0.0001 | <0.0001 |
| Methylxanthines | 736 | (0.3) | 3122 | (8.0) | 1373 | (17.3) | <0.0001 | <0.0001 |
| Beta2-adrenergic agonist | 38200 | (16.6) | 23517 | (60.3) | 6932 | (87.5) | <0.0001 | <0.0001 |
| Systemic corticosteroids | 4121 | (1.8) | 9730 | (25.0) | 5219 | (65.9) | <0.0001 | <0.0001 |
| Anticholinergics | 63782 | (27.7) | 31115 | (79.8) | 7312 | (92.3) | <0.0001 | <0.0001 |
| Inhaled corticosteroids | 55318 | (24.0) | 20939 | (53.7) | 5954 | (75.1) | <0.0001 | <0.0001 |
COPD = chronic obstructive pulmonary disease; COPDe = chronic obstructive pulmonary disease exacerbations. PVD = peripheral vascular disease.
a Chi-square tests for stroke patients had no COPD, COPDne, and COPDe.
b Chi-square tests between patients with COPDne and patients with COPDe.