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. 2017 Jan 6;12(1):e0169429. doi: 10.1371/journal.pone.0169429

Table 4. Risks of complications and mortality during stroke hospitalization associated with COPD and COPD exacerbations.

No COPD COPDne COPDe Risk of outcomes for COPDne Risk of outcomes for COPDe
n (%) n (%) n (%) OR (95% CI)c OR (95% CI)c
Number 230553 38997 7924
Mortality 7827 (3.4) 1373 (3.5) 344 (4.3) 1.14 (1.07–1.22) 1.34 (1.20–1.52)
Epilepsy 3786 (1.6) 798 (2.1) 192 (2.4) 1.27 (1.17–1.38) 1.43 (1.22–1.67)
Pneumonia 12877 (5.6) 3353 (8.6) 921 (11.6) 1.24 (1.18–1.29) 1.50 (1.39–1.62)
Acute myocardial infarction 1846 (0.8) 337 (0.9) 79 (1.0) 0.90 (0.80–1.02) 0.92 (0.72–1.16)
Gastrointestinal bleeding 5563 (2.4) 1087 (2.8) 245 (3.1) 0.98 (0.91–1.05) 0.97 (0.85–1.11)
Urinary tract infection 21071 (9.1) 4027 (10.3) 849 (10.7) 1.02 (0.98–1.06) 1.06 (0.98–1.14)
Adverse eventsa 22672 (9.8) 5051 (13.0) 1335 (16.9) 1.23 (1.19–1.28) 1.55 (1.42–1.63)
Length of stay, daysb 8.6±7.0 8.5±6.8 9.3±7.1 0.0048 <0.0001

CI = confidence interval; COPD = chronic obstructive pulmonary disease; COPDe = chronic obstructive pulmonary disease exacerbations; OR = odds ratio.

a Adverse events include pneumonia, epilepsy and mortality

b Mean±SD

c Adjusted for all covariates listed in Table 3 except for respiratory medications.