Table 1. Individual functional CEUS values.
| Animal No. | WiAUC [a.u.] | |
|---|---|---|
| Day 0 | Day 7 | |
| THERAPY GROUP | ||
| 1 | n/a | n/a |
| 2 | 102,709 | 29,476 |
| 3 | 50,150 | 39,784 |
| 4 | 47,518 | 7,779 |
| 5 | 282,576 | 5,463 |
| 6 | 200,592 | 19,290 |
| 7 | 69,803 | 31,530 |
| 8 | 82,944 | 7,070 |
| 9 | 66,663 | 39,336 |
| 10 | 94,354 | 22,951 |
| 11 | 172,584 | 98,085 |
| Mean | 116,989* | 30,076*/# |
| SD | 77,048 | 27,095 |
| CONTROL GROUP | ||
| 12 | n/a | n/a |
| 13 | 92,930 | 69,166 |
| 14 | 232,554 | 85,876 |
| 15 | 117,899 | 261,323 |
| 16 | n/a | n/a |
| 17 | 116,438 | 78,529 |
| 18 | 53,246 | 23,437 |
| 19 | 118,856 | 48,542 |
| 20 | 102,021 | 49,414 |
| 21 | 237,511 | 58,243 |
| Mean | 133,932 | 84,316# |
| SD | 65,960 | 74,144 |
Individual functional CEUS values of tumor microcirculation in subcutaneous human colon carcinoma xenografts at baseline and follow-up in the therapy and in the control group. Note the significant decrease of WiAUC between day 0 and day 7 in the therapy group as well as the significantly lower mean WiAUC values in the therapy than in the control group at follow-up.
* significant difference (p < 0.01) between baseline and follow-up
# significant difference (p < 0.01) between therapy and control group
n/a = not available due to technical issues