Table 3. Individual DCE-MRI values.
| Animal No. | PF [mL/100mL/min] | PV [%] | ||
|---|---|---|---|---|
| Day 0 | Day 7 | Day 0 | Day 7 | |
| THERAPY GROUP | ||||
| 1 | 140 | 48 | 9 | 6 |
| 2 | 96 | 79 | 9 | 3 |
| 3 | 114 | 86 | 10 | 11 |
| 4 | 195 | 63 | 13 | 10 |
| 5 | 213 | 77 | 10 | 17 |
| 6 | 249 | 86 | 15 | 11 |
| 7 | 130 | 78 | 12 | 9 |
| 8 | 123 | 64 | 12 | 8 |
| 9 | 81 | 47 | 13 | 7 |
| 9 | 201 | 90 | 14 | 5 |
| 11 | 78 | 61 | 20 | 7 |
| Mean | 147* | 71*/# | 13* | 9*/# |
| SD | 58 | 15 | 3 | 4 |
| CONTROL GROUP | ||||
| 12 | 155 | 99 | 8 | 10 |
| 13 | 93 | 114 | 8 | 15 |
| 14 | 94 | 112 | 8 | 7 |
| 15 | 110 | 139 | 17 | 26 |
| 16 | 140 | 124 | 14 | 10 |
| 17 | n/a | n/a | n/a | n/a |
| 18 | 107 | 46 | 24 | 14 |
| 19 | 86 | 156 | 20 | 12 |
| 20 | 102 | 125 | 15 | 28 |
| 21 | 86 | 100 | 12 | 21 |
| Mean | 108 | 113# | 14 | 16# |
| SD | 24 | 31 | 6 | 8 |
Individual DCE-MRI parameters of tumor microcirculation with tumor plasma flow (PF; mL/100mL/min) and plasma volume (PV; %) at baseline and follow-up in the therapy and in the control group. Note the significant decrease of tumor microcirculatory parameters PF and PV between day 0 and day 7 as well as the significantly lower mean values of PF and PV in the therapy than in the control group at the follow-up.
* significant difference (p < 0.05) between baseline and follow-up
# significant difference (p < 0.03) between therapy and control group
n/a = not available due to technical issues