TABLE 1.
siRNA | Exon | Sequence (5′ to 3′) |
---|---|---|
siRNA2 | I | AACAGCTGAGAGGCCTTGGAT |
siRNA3 | II | AACTCCTCTCCTTCACGCTCT |
siRNA8 | III | AAGACGCGATCTACCAGAACC |
siRNA11 | III | AAGGCTGCAGTGGGTGAGCTT |
siRNA26 | IV | AACTGGCACGACTCCATCACC |
siRNA35 | VI | AAGACTGCGCGGAATTTAGTG |
Six different siRNAs directed against human DC-SIGN were designed to correspond to distinct parts of the DC-SIGN mRNA sequence. Target sequences of the DC-SIGN cDNA and corresponding exons are shown.