Table 1. Characteristics of Participants for thiamine-metabolizing enzymes assay (mean± SD).
Characteristics(mean± SD) | AD patients(n = 45) | Control subjects(n = 38) | P value |
---|---|---|---|
Male/Female | 19/26 | 19/19 | 0.514 |
Age (year) | 79.20±6.42 (63–89) | 78.71±6.72 (63–89) | 0.736 |
Education (year) | 5.00±4.54 (0–16) | 5.76±4.86 (0–16) | 0.462 |
MMSE scores | 5.62±6.28 (0–21) | 27.08±2.24 (23–30) | <0.0001 |
TDP (nmol/L) | 79.03±23.24(41.05–160.60) | 127.60±22.65(77.76–187.50) | <0.0001 |
TMP (nmol/L) | 5.33±4.44 (0–19.22) | 3.81±2.91(0.28–14.33) | 0.077 |
Thiamine (nmol/L) | 3.62±3.87(0.53–19.35) | 3.95±3.59(0.50–21.45) | 0.691 |
ApoE ε4 allele (%) | 24 (53.33) | 3 (7.89) | <0.0001 |
Fasting Blood glucose (mmol/L) | 5.43±1.52 (3.50–9.23) | 6.13±1.51(4.81–13.88) | <0.05 |