FIG. 2.

Example of inhibition curve showing licochalcone A inhibition of growth of P. falciparum strain 3D7 cultured in human erythrocytes, as expressed by incorporation of [³H]phenylalanine (49). In this particular determination, an IC₅₀ of 2.02 ± 0.19 μg of licochalcone A/ml (5.97 ± 0.56 μM) is obtained. The IC₅₀ of chloroquine diphosphate determined under identical conditions was 28.3 ± 13.2 ng/ml or 0.055 ± 0.025 μM.