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. Author manuscript; available in PMC: 2017 Jan 6.
Published in final edited form as: Biomed Pharmacother. 2016 Nov 26;85:399–411. doi: 10.1016/j.biopha.2016.11.043

Fig. 4.

Fig. 4

A continuous presence of Estradiol has an opposite effect compared to a hormonal imbalance simulation. (A) Morphological evaluation of CSC-enriched cell cultures after 1 and 10 nmol l−1 continuous E2 treatment, and with hormonal imbalance simulation (magnitude 10×; optical microscope). (B) Mean Fluoresce Index of FACS analysis for SOX2, OCT3, NANOG, ERA, ERB, and GPER1. UNTREAT = control; E2 TREAT = cells after 7-days treatment; STOPPING TREAT = cells after stopping treatment for further 7 days. * = P < 0.005.