TABLE 3.

Effect of the nontoxic microbicide and placebo formulations on long-term epithelial cell line viability

Product	% Viability of epithelial cell linesa
	Caco-2	SW837	HEC-1-A	ME-180
CAP	90	102	85	134
Carraguardb	50	71	ND	ND
Methylcellulose	99	78	82	142
PRO 2000 4%	89	79	73	112
PRO 2000 0.5%	94	80	94	110
PRO 2000 placebo	82	100	93	108
KY-N9	96	85	71	83
KY Jelly	99	68	72	99
SPL7013 5%	58	NDc	68	ND
SPL7013 placebo	76	ND	72	ND
UC781 1%	94	89	85	109
UC781 0.1%	90	77	94	80
UC781 placebo	88	89	85	109
Vena Gel	65	92	76	80
Vena Gel placebo	84	65	90	91

^aEpithelial cells were exposed to the 24-hour nontoxic concentration of each product for 2 h a day for 5 days. Percent viability shown was determined on the fifth day.

^bPercent viability of Carraguard was determined by trypan blue exclusion.

^cND, not determined.