IL-6 (A) and IL-8 (B) were assayed by ELISA in plasma samples from patients with staphylococcal sepsis and are displayed by TLR4 variant rs1927907 genotype. Boxes show the median and interquartile range; whiskers show upper and lower adjacent values; outside values are not shown for clarity. Values were log10 transformed and linear regression was performed using a recessive model (comparing CC and CT subjects to TT subjects), adjusting for age, sex, comorbidity index, and site. N=249 (CC), 69 (CT), 6 (TT). **, P ≤ 0.01; *, P < 0.05.