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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Clin Microbiol Infect. 2016 Sep 8;23(1):47.e1–47.e10. doi: 10.1016/j.cmi.2016.08.028

Table 3.

Association of TLR4 variant rs1927907 with clinical outcomes of patients with staphylococcal sepsis

Genotype Respiratory failure Shock Death
Yes No Yes No Yes No
CC 42
(72%)		 210
(78%)		 29
(76%)		 223
(77%)		 22
(73%)		 230
(77%)
CT 12
(21%)		 57
(21%)		 7
(18%)		 62
(21%)		 7
(23%)		 62
(21%)
TT 4
(7%)		 2
(1%)		 2
(5%)		 4
(1%)		 1
(3%)		 5
(2%)
Unadjusted P valuea 0.018 0.22 0.51
Adjusted OR (95% CI) 9.65 (1.60–58.08) 4.31 (0.66–27.96) 1.75 (0.18–17.11)
Adjusted P valueb 0.01 0.13 0.63
a

Unadjusted analyses are performed using the exact test

b

Adjusted analyses are performed using logistic regression assuming a recessive genetic model adjusting for age, sex, co-morbidity index, and site.