Table 3.
Prevalence of NAFLD % (95% CI) |
Percentage of NAFLD with elevated liver enzymes |
Hepatic steatosis compared to controls | ||
---|---|---|---|---|
aOR* (95% CI) | p value | |||
Metabolic syndrome | 43.2 (39.4 – 46.9) | 19.9% (1.9) | 11.5 (8.9 – 14.7) | <0.001 |
Three abnormalities | 37.3 (33.7 – 41.0) | 18.1% (2.4) | 9.7 (7.6 – 12.5) | <0.001 |
Four abnormalities | 48.5 (43.9 – 53.1) | 21.6% (3.8) | 16.9 (12.0 – 23.8) | <0.001 |
Five abnormalities | 67.3 (56.7 – 77.8) | 22.8% (4.5) | 37.6 (25.0 – 56.3) | <0.001 |
Increased WC† | 31.2 (28.6 – 33.9) | 17.1% (1.6) | 2.9 (2.2 – 3.8) | <0.001 |
IFG/Diabetes† | 41.2 (36.6 – 45.9) | 20.3% (2.8) | 2.0 (1.2 – 3.4) | 0.007 |
High Triglyceride level† | 34.7 (31.8 – 37.6) | 19.0% (2.1) | 2.2 (1.5 – 3.0) | <0.001 |
Low HDL level† | 27.8 (25.1 – 30.4) | 17.6% (2.0) | 1.5 (1.2 – 1.9) | <0.001 |
High BP† | 29.2 (26.5 – 31.9) | 17.9% (1.9) | 1.3 (0.9 – 1.8) | 0.060 |
Abbreviations: NAFLD – nonalcoholic fatty liver disease, WC – waist circumference, IFG – impaired fasting glucose, HDL – high density lipoprotein,
aOR – adjusted odds ratio (adjusted for age, sex, race, smoking, alcohol use, and education level), CI – confidence interval, S.E. – standard error of percentage
Odds ratio further adjusted for other metabolic abnormalities