Table 2. Comparison of findings.
| Variable | Liraglutide (4) | Other TZD’s (5) | Vitamin E (5) | OCA (5) | Pentoxifylline (5) |
|---|---|---|---|---|---|
| Improved fibrosis | X | X | |||
| No worsening fibrosis | X | ||||
| Decrease BMI | X | Increase BMI | X | X | |
| NAFL score improvement | No | ||||
| Hepatocyte ballooning score improvement | X | X | X | X | |
| Lobular inflammation score improvement | X | X | X | ||
| Steatosis improvement | X | X | X | X | |
| Resolution of non-alcoholic steatohepatitis post biopsy | X | ||||
| Possible medication issues i.e., toxicities | GI side effects | Weight gain, cardiovascular | Prostate issues, increased CV mortality |
X, the finding is present in listed variable, for indicated medication. TZD, thiazolidinediones; OCA, obeticholic acid.