Table 2. Comparison of findings.
Variable | Liraglutide (4) | Other TZD’s (5) | Vitamin E (5) | OCA (5) | Pentoxifylline (5) |
---|---|---|---|---|---|
Improved fibrosis | X | X | |||
No worsening fibrosis | X | ||||
Decrease BMI | X | Increase BMI | X | X | |
NAFL score improvement | No | ||||
Hepatocyte ballooning score improvement | X | X | X | X | |
Lobular inflammation score improvement | X | X | X | ||
Steatosis improvement | X | X | X | X | |
Resolution of non-alcoholic steatohepatitis post biopsy | X | ||||
Possible medication issues i.e., toxicities | GI side effects | Weight gain, cardiovascular | Prostate issues, increased CV mortality |
X, the finding is present in listed variable, for indicated medication. TZD, thiazolidinediones; OCA, obeticholic acid.