Table 3.
Anthelmintic activity data of synthesized compounds 3a–d, 4a–d and 5a–l
| Comp | Paralytic time (min)a | Death time (min)a | ||||
|---|---|---|---|---|---|---|
| Concentration (%) | Concentration (%) | |||||
| 1 | 2 | 3 | 1 | 2 | 3 | |
| 3a | 12.17 ± 1.08 | 11.05 ± 1.28 | 10.30 ± 1.02 | 22.15 ± 0.75 | 20.25 ± 0.38 | 18.25 ± 0.64 |
| 3b | 12.52 ± 1.03 | 11.40 ± 1.21 | 11.05 ± 0.78 | 23.20 ± 0.39 | 21.38 ± 1.12 | 19.35 ± 0.82 |
| 3c | 13.35 ± 0.98 | 11.40 ± 1.05 | 11.15 ± 1.18 | 23.35 ± 1.13 | 21.24 ± 0.83 | 20.35 ± 0.73 |
| 3d | 13.55 ± 0.68 | 12.40 ± 0.58 | 11.35 ± 0.88 | 23.20 ± 1.14 | 21.52 ± 1.12 | 21.39 ± 1.21 |
| 4a | 27.54 ± 0.41 | 25.42 ± 0.72 | 23.41 ± 0.51 | 38.40 ± 0.53 | 35.27 ± 0.57 | 33.25 ± 1.05 |
| 4b | 28.57 ± 0.41 | 25.52 ± 0.72 | 23.35 ± 0.51 | 39.45 ± 0.53 | 35.57 ± 0.57 | 33.39 ± 1.05 |
| 4c | 29.47 ± 0.41 | 26.42 ± 0.72 | 24.31 ± 0.51 | 41.38 ± 0.53 | 37.53 ± 0.57 | 34.29 ± 1.05 |
| 4d | 30.41 ± 0.41 | 27.47 ± 0.72 | 24.53 ± 0.51 | 42.35 ± 0.53 | 38.43 ± 0.57 | 35.32 ± 1.05 |
| 5a | 19.58 ± 0.36 | 18.00 ± 1.07 | 15.54 ± 0.94 | 30.56 ± 0.45 | 28.55 ± 0.67 | 25.57 ± 0.92 |
| 5b | 19.43 ± 0.59 | 17.54 ± 0.24 | 15.28 ± 0.30 | 30.10 ± 0.25 | 28.34 ± 0.47 | 25.32 ± 0.58 |
| 5c | 19.58 ± 0.36 | 18.00 ± 1.07 | 15.54 ± 0.94 | 30.56 ± 0.45 | 28.55 ± 0.67 | 25.57 ± 0.92 |
| 5d | 23.47 ± 0.41 | 20.57 ± 0.72 | 18.52 ± 0.51 | 34.50 ± 0.53 | 30.58 ± 0.57 | 28.49 ± 1.05 |
| 5e | 23.58 ± 0.41 | 21.38 ± 0.72 | 19.52 ± 0.51 | 35.30 ± 0.53 | 31.43 ± 0.57 | 29.44 ± 1.05 |
| 5f | 26.29 ± 0.41 | 23.46 ± 0.72 | 21.31 ± 0.51 | 36.33 ± 0.53 | 33.41 ± 0.57 | 31.30 ± 1.05 |
| 5 g | 24.55 ± 0.41 | 22.56 ± 0.72 | 20.42 ± 0.51 | 35.42 ± 0.53 | 32.51 ± 0.57 | 30.10 ± 1.05 |
| 5 h | 27.19 ± 0.41 | 24.36 ± 0.72 | 22.21 ± 0.51 | 37.43 ± 0.53 | 34.37 ± 0.57 | 32.15 ± 1.05 |
| 5i | 13.58 ± 0.58 | 12.56 ± 0.63 | 11.48 ± 0.84 | 23.38 ± 0.67 | 22.00 ± 0.91 | 21.46 ± 0.49 |
| 5j | 18.42 ± 0.38 | 17.11 ± 0.57 | 14.42 ± 0.67 | 29.42 ± 0.82 | 26.52 ± 1.04 | 24.12 ± 0.83 |
| 5 k | 15.12 ± 0.25 | 14.11 ± 0.74 | 12.54 ± 0.62 | 25.14 ± 0.57 | 23.34 ± 0.43 | 22.15 ± 0.73 |
| 5 l | 23.24 ± 0.41 | 20.35 ± 0.72 | 18.44 ± 0.51 | 34.32 ± 0.53 | 30.45 ± 0.57 | 28.38 ± 1.05 |
| Std | 10.37 ± 1.08 | 09.41 ± 0.64 | 08.17 ± 0.38 | 20.20 ± 0.94 | 18.15 ± 0.68 | 16.18 ± 0.83 |
Std albendazole
aMean ± SEM, n = 6