Fig. 6.

Diverse forms of centriolar satellites in the context of various cues and cell cycle stages. Centriolar satellite integrity is regulated by many factors. Centriolar satellite organisation is changed during the cell cycle. Centriolar satellite integrity is structurally and functionally linked to other cellular processes including autophagy. In addition, centriole satellites undergo drastic remodelling in response to various cellular stresses. A cohort of protein kinases including PLK4 and p38-MK2 are involved in centriolar satellite integrity, which plays a pivotal role in centriole/centrosome assembly and ciliogenesis. See text for details